The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease

The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease

Kidney disease is worldwide the 12th leading cause of death affecting 8–16% of the entire population. Kidney disease encompasses acute (short-lasting episode) and chronic (developing over years) pathologies both leading to renal failure. Since specific treatments for acute or chronic kidney disease...

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Bibliographic Details
Main Authors: Pasquale Cocchiaro, Valeria De Pasquale, Rossella Della Morte, Simona Tafuri, Luigi Avallone, Anne Pizard, Anna Moles, Luigi Michele Pavone
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cathepsins
acute kidney injury
chronic kidney disease
lysosomal proteases
signaling pathways
Online Access:http://journal.frontiersin.org/article/10.3389/fcell.2017.00114/full

Internet

http://journal.frontiersin.org/article/10.3389/fcell.2017.00114/full

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