Role of circulating endothelial cells in assessing the severity of systemic sclerosis and predicting its clinical worsening

Abstract Endothelial damage and fibro-proliferative vasculopathy of small vessels are pathological hallmarks of systemic sclerosis (SSc). The consequence is the detachment of resident elements that become circulating endothelial cells (CECs). The aim of our study was to evaluate the potential of CEC...

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Bibliographic Details
Main Authors: Maria Luisa Di Martino, Alessandra Frau, Francesca Losa, Emma Muggianu, Mario Nicola Mura, Gianluca Rotta, Lorenza Scotti, Francesco Marongiu
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80604-7