ATF3 Prevents Stress-Induced Hematopoietic Stem Cell Exhaustion

Protection of hematopoietic stem cells (HSCs) from exhaustion and effective regeneration of the HSC pool after bone marrow transplantation or irradiation therapy is an urgent clinical need. Here, we investigated the role of activating transcription factor 3 (ATF3) in steady-state and stress hematopo...

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Bibliographic Details
Main Authors: Yufeng Liu, Yingying Chen, Xiaohui Deng, Jie Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.585771/full