Aurora A drives early signalling and vesicle dynamics during T-cell activation

Aurora A drives early signalling and vesicle dynamics during T-cell activation

Aurora A is a protein kinase that contributes to the progression of mitosis by stimulating microtubule nucleation. Here the authors show that Aurora A also functions during T cell activation by maintaining TCR signaling through Lck activation.

Bibliographic Details
Main Authors: Noelia Blas-Rus, Eugenio Bustos-Morán, Ignacio Pérez de Castro, Guillermo de Cárcer, Aldo Borroto, Emilio Camafeita, Inmaculada Jorge, Jesús Vázquez, Balbino Alarcón, Marcos Malumbres, Noa B. Martín-Cófreces, Francisco Sánchez-Madrid
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11389

Internet

https://doi.org/10.1038/ncomms11389

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