Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells.

The androgen receptor (AR) is expressed in a subset of prostate stromal cells and functional stromal cell AR is required for normal prostate developmental and influences the growth of prostate tumors. Although we are broadly aware of the specifics of the genomic actions of AR in prostate cancer cell...

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Bibliographic Details
Main Authors: Matthew J Tanner, R Charles Welliver, Mengqian Chen, Michael Shtutman, Alejandro Godoy, Gary Smith, Badar M Mian, Ralph Buttyan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3022749?pdf=render