Swimming in Deep Water: Zebrafish Modeling of Complicated Forms of Hereditary Spastic Paraplegia and Spastic Ataxia

Swimming in Deep Water: Zebrafish Modeling of Complicated Forms of Hereditary Spastic Paraplegia and Spastic Ataxia

Hereditary spastic paraplegia (HSP) and hereditary ataxia (HA) are two groups of disorders characterized, respectively, by progressive dysfunction or degeneration of the pyramidal tracts (HSP) and of the Purkinje cells and spinocerebellar tracts (HA). Although HSP and HA are generally shown to have...

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Bibliographic Details
Main Authors: Valentina Naef, Serena Mero, Gianluca Fichi, Angelica D'Amore, Asahi Ogi, Federica Gemignani, Filippo M. Santorelli, Maria Marchese
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Neuroscience
Subjects:
zebrafish
hereditary ataxia (HA)
hereditary spastic paraplegia (HSP)
neurodegenerative disorders
motor neuron disease
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01311/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01311/full

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