Mucosal-Associated Invariant T Cell Levels Are Reduced in the Peripheral Blood and Lungs of Children With Active Pulmonary Tuberculosis

Mucosal-Associated Invariant T Cell Levels Are Reduced in the Peripheral Blood and Lungs of Children With Active Pulmonary Tuberculosis

Mucosal associated invariant T (MAIT) cells are unconventional, semi-invariant T lymphocytes that recognize microbial-derived vitamin B2 (riboflavin) biosynthesis precursor derivatives presented by the monomorphic MHC class 1-related (MR1) molecule. Upon microbial infection, MAIT cells rapidly produ...

Full description

Bibliographic Details
Main Authors: Clara Malka-Ruimy, Ghada Ben Youssef, Marion Lambert, Marie Tourret, Liana Ghazarian, Albert Faye, Sophie Caillat-Zucman, Véronique Houdouin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
mucosal associated invariant T cells
innate immune response
microbial infection
host pathogen interactions
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00206/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00206/full

Similar Items