Association with amino acids does not enhance efficacy of polymerized liposomes as a system for lung gene delivery

Association with amino acids does not enhance efficacy of polymerized liposomes as a system for lung gene delivery

Development of improved drug and gene delivery systems directly into the lungs is highly desirable given the important burden of respiratory diseases. We aimed to evaluate the safety and efficacy of liposomes composed of photopolymerized lipids (1,2-bis-(tricosa-10,12-diynoyl)-sn-glycero-3-phosphoch...

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Bibliographic Details
Main Authors: Elga eBernardo Bandeira De Melo, Miquéias eLopes-Pacheco, Nadia eChiaramoni, Débora eFerreira, Maria Julieta eFernandez-Ruocco, Maria Jimena ePrieto, Tatiana eMaron-Gutierrez, Ramiro M Perrotta, Hugo C Castro-Faria-Neto, Patricia Rieken Macedo Rocco, Silvia del Valle Alonso, Marcelo Marcos Morales
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Physiology
Subjects:
Inflammation
Lung
Nanoparticles
gene delivery
Mechanic parameters
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00151/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00151/full

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