ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation

ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation

Innate lymphoid cells (ILCs) contribute to host defence and tissue repair but can induce immunopathology. Recent work has revealed tissue-specific roles for ILCs; however, the question of how a small population has large effects on immune homeostasis remains unclear. We identify two mechanisms that...

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Bibliographic Details
Main Authors: Claire Pearson, Emily E Thornton, Brent McKenzie, Anna-Lena Schaupp, Nicky Huskens, Thibault Griseri, Nathaniel West, Sim Tung, Benedict P Seddon, Holm H Uhlig, Fiona Powrie
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-01-01
Series:eLife
Subjects:
live imaging
innate lymphoid cell
mucosal immunology
colitis
Online Access:https://elifesciences.org/articles/10066

Internet

https://elifesciences.org/articles/10066

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