Nanotracing and cavity-ring down spectroscopy: A new ultrasensitive approach in large molecule drug disposition studies.

New therapeutic biological entities such as bispecific antibodies targeting tissue or specific cell populations form an increasingly important part of the drug development portfolio. However, these biopharmaceutical agents bear the risk of extensive target-mediated drug disposition or atypical pharm...

Full description

Bibliographic Details
Main Authors: Nicole A Kratochwil, Stephen R Dueker, Dieter Muri, Claudia Senn, HyeJin Yoon, Byung-Yong Yu, Gwan-Ho Lee, Feng Dong, Michael B Otteneder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6192596?pdf=render