Reduced membrane attack complex formation in umbilical cord blood during Eculizumab treatment of the mother: a case report

Reduced membrane attack complex formation in umbilical cord blood during Eculizumab treatment of the mother: a case report

Abstract Background Atypical hemolytic uremic syndrome (aHUS) is a disorder of the microvasculature with hemolytic anemia, thrombocytopenia and acute kidney injury. Nowadays, aHUS is successfully treated with eculizumab, a humanized, chimeric IgG2/4 kappa antibody, which binds human complement C5 an...

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Bibliographic Details
Main Authors: Subagini Nagarajah, Martin Tepel, Christian Nielsen, Kristian Assing, Yaseelan Palarasah, Lise Lotte Torvin Andersen, Lotte Borg Lange, Claus Bistrup
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Nephrology
Subjects:
Atypical hemolytic uremic syndrome
End-stage renal disease
Pregnancy
Complement
Eculizumab
Umbilical cord vein blood
Online Access:http://link.springer.com/article/10.1186/s12882-019-1469-9

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http://link.springer.com/article/10.1186/s12882-019-1469-9

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