MicroRNA-145 Involves in the Pathogenesis of Renal Vascular Lesions and May Become a Potential Therapeutic Target in Patients with Juvenile Lupus Nephritis

MicroRNA-145 Involves in the Pathogenesis of Renal Vascular Lesions and May Become a Potential Therapeutic Target in Patients with Juvenile Lupus Nephritis

Aims: The current study was conducted with the central objective of investigating the expression of microRNA-145 (miR-145) in renal vascular lesions (RVLs) in juvenile lupus nephritis (JLN) and its possible mechanism. Methods: The clinical data of 49 JLN patients confirmed by renal biopsy were colle...

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Bibliographic Details
Main Authors: Zhaomin Cai, Wei Xiang, Xiaojie Peng, Yan Ding, Wang Liao, Xiaojie He
Format: Article
Language:English
Published: Karger Publishers 2019-08-01
Series:Kidney & Blood Pressure Research
Subjects:
Systemic lupus erythematosus
Lupus nephritis
MicroRNA-145
Renal vascular lesion
Human vascular smooth muscle cells
PDGF-BB
Online Access:https://www.karger.com/Article/FullText/500923

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https://www.karger.com/Article/FullText/500923

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