Exploring the Complementarity of Pancreatic Ductal Adenocarcinoma Preclinical Models

Exploring the Complementarity of Pancreatic Ductal Adenocarcinoma Preclinical Models

<i>Purpose</i>: Compare pancreatic ductal adenocarcinoma (PDAC), preclinical models, by their transcriptome and drug response landscapes to evaluate their complementarity. <i>Experimental Design</i>: Three paired PDAC preclinical models—patient-derived xenografts (PDX), xenog...

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Bibliographic Details
Main Authors: Owen Hoare, Nicolas Fraunhoffer, Abdessamad Elkaoutari, Odile Gayet, Martin Bigonnet, Julie Roques, Rémy Nicolle, Colin McGuckin, Nico Forraz, Emilie Sohier, Laurie Tonon, Pauline Wajda, Sandrine Boyault, Valéry Attignon, Séverine Tabone-Eglinger, Sandrine Barbier, Caroline Mignard, Olivier Duchamp, Juan Iovanna, Nelson J. Dusetti
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
pancreatic cancer
chemosensitivity prediction
personalized medicine
in vivo models
in vitro models
Online Access:https://www.mdpi.com/2072-6694/13/10/2473

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https://www.mdpi.com/2072-6694/13/10/2473

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