The zinc finger transcription factor, KLF2, protects against COVID-19 associated endothelial dysfunction

Abstract Coronavirus disease 2019 (COVID-19) is regarded as an endothelial disease (endothelialitis) with its patho-mechanism being incompletely understood. Emerging evidence has demonstrated that endothelial dysfunction precipitates COVID-19 and its accompanying multi-organ injuries. Thus, pharmaco...

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Bibliographic Details
Main Authors: Suowen Xu, Yujie Liu, Yu Ding, Sihui Luo, Xueying Zheng, Xiumei Wu, Zhenghong Liu, Iqra Ilyas, Suyu Chen, Shuxin Han, Peter J. Little, Mukesh K. Jain, Jianping Weng
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00690-5

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