Synthesis and Comparison of In Vitro Leishmanicidal Activity of 5-(Nitroheteroaryl)-1, 3, 4-Thiadiazols Containing Cyclic Amine of Piperidin-4-ol at C-2 with Acyclic Amine Analogues against Iranian Strain of Leishmania major (MRHO/IR/75/ER)

Synthesis and Comparison of In Vitro Leishmanicidal Activity of 5-(Nitroheteroaryl)-1, 3, 4-Thiadiazols Containing Cyclic Amine of Piperidin-4-ol at C-2 with Acyclic Amine Analogues against Iranian Strain of Leishmania major (MRHO/IR/75/ER)

Background: Cutaneous Leishmaniasis (CL) is endemic in many tropical and subtropical regions of the world. Due to the prolonged duration of therapy, adverse effect and resistance to current drugs in the treatment of CL, the dis­covery of novel, efficient, and safe leishmanicidal drugs is required....

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Bibliographic Details
Main Authors: Azar Tahghighi, Alireza Foroumadi, Susan Kabudanian Ardestani, Seyed Mohammad Amin Mahdian
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-04-01
Series:Journal of Arthropod-Borne Diseases
Subjects:
Leishmania major
Thiadiazole
Nitrofuran
Nitrothiophen
Superimpose
Online Access:https://jad.tums.ac.ir/index.php/jad/article/view/461

Internet

https://jad.tums.ac.ir/index.php/jad/article/view/461

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