MANF Produced by MRL Mouse-Derived Mesenchymal Stem Cells Is Pro-regenerative and Protects From Osteoarthritis

MANF Produced by MRL Mouse-Derived Mesenchymal Stem Cells Is Pro-regenerative and Protects From Osteoarthritis

The super healer Murphy Roths Large (MRL) mouse represents the “holy grail” of mammalian regenerative model to decipher the key mechanisms that underlies regeneration in mammals. At a time when mesenchymal stem cell (MSC)-based therapy represents the most promising approach to treat degenerative dis...

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Bibliographic Details
Main Authors: Gautier Tejedor, Patricia Luz-Crawford, Audrey Barthelaix, Karine Toupet, Sébastien Roudières, François Autelitano, Christian Jorgensen, Farida Djouad
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
MRL mouse
regeneration
mesenchymal stem cells
MANF
chondroprotection
osteoarthritis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.579951/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.579951/full

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