Integrated Fecal Microbiome and Serum Metabolomics Analysis Reveals Abnormal Changes in Rats with Immunoglobulin A Nephropathy and the Intervention Effect of Zhen Wu Tang

Integrated Fecal Microbiome and Serum Metabolomics Analysis Reveals Abnormal Changes in Rats with Immunoglobulin A Nephropathy and the Intervention Effect of Zhen Wu Tang

Immunoglobulin A nephropathy (IgAN), an autoimmune renal disease with complicated pathogenesis, is one of the principal reasons for end-stage renal disease in the clinic. Evidence has linked apparent alterations in the components of the microbiome and metabolome to renal disease in rats. However, th...

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Bibliographic Details
Main Authors: Jicheng Li, Yiwen Cao, Ruirui Lu, Honglian Li, Yu Pang, Hongxin Fu, Guoxing Fang, Qiuhe Chen, Bihao Liu, Junbiao Wu, Yuan Zhou, Jiuyao Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
kidney injury
immune inflammation
metabolism
gut microbiota
Zhen Wu Tang
immunoglobulin A nephropathy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.606689/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.606689/full

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