Activity of meropenem/vaborbactam against international carbapenem-resistant Escherichia coli isolates in relation to clonal background, resistance genes, resistance to comparators and region

Activity of meropenem/vaborbactam against international carbapenem-resistant Escherichia coli isolates in relation to clonal background, resistance genes, resistance to comparators and region

Objectives: Carbapenem resistance has emerged inEscherichia coli, including sequence type 131 (ST131) and its fluoroquinolone-resistant H30R subclone, the leading cause of extraintestinal E. coli infections globally. Meropenem/vaborbactam (MVB) is a recently approved carbapenem/β-lactamase inhibitor...

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Bibliographic Details
Main Authors: Brian D. Johnston, Paul Thuras, Stephen B. Porter, Mariana Castanheira, James R. Johnson
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Escherichia coli
Carbapenem resistance
ST131
Meropenem/vaborbactam
Klebsiella pneumoniae carbapenemase
New Delhi metallo-β-lactamase
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716521000023

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http://www.sciencedirect.com/science/article/pii/S2213716521000023

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