Uncoupling of natural IgE production and CD23 surface expression levels.

CD23, the low affinity receptor for immunoglobulin E (IgE), has been proposed to play a critical role in the regulation of IgE production, based on altered IgE levels in CD23-deficient mice and transgenic mouse models, as well as in mouse strains with mutations in the CD23 gene, e.g. 129 substrains....

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Bibliographic Details
Main Authors: Weicheng Ren, Kristina Lagerstedt, Ola Grimsholm, Anna Stern, Jia-Bin Sun, Yu Fang, Zou Xiang, Inga-Lill Mårtensson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3639908?pdf=render