Myeloid transformation of plasma cell myeloma: molecular evidence of clonal evolution revealed by next generation sequencing

Myeloid transformation of plasma cell myeloma: molecular evidence of clonal evolution revealed by next generation sequencing

Abstract Background Plasma cell myeloma (PCM) is a neoplasm of terminally differentiated B lymphocytes with molecular heterogeneity. Although therapy-related myeloid neoplasms are common in plasma cell myeloma patients after chemotherapy, transdifferentiation of plasma cell myeloma into myeloid neop...

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Bibliographic Details
Main Authors: Jonathon H. Gralewski, Ginell R. Post, Frits van Rhee, Youzhong Yuan
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Diagnostic Pathology
Subjects:
Clonal evolution
Myeloid sarcoma
Molecular profiling
Next generation sequencing
Transdifferentiation
Plasma cell myeloma
Online Access:http://link.springer.com/article/10.1186/s13000-018-0692-1

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http://link.springer.com/article/10.1186/s13000-018-0692-1

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