Molecular basis of efficient replication and pathogenicity of H9N2 avian influenza viruses in mice.

H9N2 subtype avian influenza viruses (AIVs) have shown expanded host range and can infect mammals, such as humans and swine. To date the mechanisms of mammalian adaptation and interspecies transmission of H9N2 AIVs remain poorly understood. To explore the molecular basis determining mammalian adapta...

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Bibliographic Details
Main Authors: Xiaokang Li, Wenbao Qi, Jun He, Zhangyong Ning, Yue Hu, Jin Tian, Peirong Jiao, Chenggang Xu, Jianxin Chen, Juergen Richt, Wenjun Ma, Ming Liao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387007?pdf=render