Regulatory BC1 RNA and the fragile X mental retardation protein: convergent functionality in brain.

BC RNAs and the fragile X mental retardation protein (FMRP) are translational repressors that have been implicated in the control of local protein synthesis at the synapse. Work with BC1 and Fmr1 animal models has revealed that phenotypical consequences resulting from the absence of either BC1 RNA o...

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Bibliographic Details
Main Authors: Jun Zhong, Shih-Chieh Chuang, Riccardo Bianchi, Wangfa Zhao, Geet Paul, Punam Thakkar, David Liu, André A Fenton, Robert K S Wong, Henri Tiedge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2990754?pdf=render