HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans

HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans

Eukaryotic cells use guided search to coordinately control dispersed genetic elements. Argonaute proteins and their small RNA cofactors engage nascent RNAs and chromatin-associated proteins to direct transcriptional silencing. The small ubiquitin-like modifier (SUMO) has been shown to promote the fo...

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Bibliographic Details
Main Authors: Heesun Kim, Yue-He Ding, Gangming Zhang, Yong-Hong Yan, Darryl Conte Jr, Meng-Qiu Dong, Craig C Mello
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
HDAC SUMOylation
nuclear argonaut
germline
Online Access:https://elifesciences.org/articles/63299

Internet

https://elifesciences.org/articles/63299

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