Comparing the cumulative live birth rate of cleavage-stage versus blastocyst-stage embryo transfers between IVF cycles: a study protocol for a multicentre randomised controlled superiority trial (the ToF trial)

Introduction In vitro fertilisation (IVF) has evolved as an intervention of choice to help couples with infertility to conceive. In the last decade, a strategy change in the day of embryo transfer has been developed. Many IVF centres choose nowadays to transfer at later stages of embryo development,...

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Main Authors: Madelon van Wely, Harold R Verhoeve, Kathrin Fleischer, Simone Cornelisse, Liliana Ramos, Brigitte Arends, Janneke J Brink-van der Vlugt, Jan Peter de Bruin, Max HJN Curfs, Josien Derhaag, Angelique van Dongen, Jannie van Echten-Arends, Eva R Groenewoud, Jacques WM Maas, Quirine Pieterse, Evert JP van Santbrink, Els Slappendel, Maaike AF Traas, Jantien Visser, Carlijn G Vergouw, Lucette AJ van der Westerlaken, Yvonne Wurth, Moniek van der Zanden, Didi DM Braat, Sebastiaan Mastenbroek
Format: Article
Language:English
Published: BMJ Publishing Group 2021-01-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/1/e042395.full