Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast.

Fanconi anemia (FA) is a devastating genetic disease, associated with genomic instability and defects in DNA interstrand cross-link (ICL) repair. The FA repair pathway is not thought to be conserved in budding yeast, and although the yeast Mph1 helicase is a putative homolog of human FANCM, yeast ce...

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Bibliographic Details
Main Authors: Thomas A Ward, Zuzana Dudášová, Sovan Sarkar, Mangesh R Bhide, Danuša Vlasáková, Miroslav Chovanec, Peter J McHugh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3415447?pdf=render