Identification of CD166 as a surface marker for enriching prostate stem/progenitor and cancer initiating cells.

New therapies for late stage and castration resistant prostate cancer (CRPC) depend on defining unique properties and pathways of cell sub-populations capable of sustaining the net growth of the cancer. One of the best enrichment schemes for isolating the putative stem/progenitor cell from the murin...

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Main Authors: Jing Jiao, Antreas Hindoyan, Shunyou Wang, Linh M Tran, Andrew S Goldstein, Devon Lawson, Donghui Chen, Yunfeng Li, Changyong Guo, Baohui Zhang, Ladan Fazli, Martin Gleave, Owen N Witte, Isla P Garraway, Hong Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3411798?pdf=render