Acanthosis nigricans as a composite marker of cardiometabolic risk and its complex association with obesity and insulin resistance in Mexican American children.

Acanthosis nigricans as a composite marker of cardiometabolic risk and its complex association with obesity and insulin resistance in Mexican American children.

<h4>Aim</h4>Acanthosis nigricans (AN) is a strong correlate of obesity and is considered a marker of insulin resistance (IR). AN is associated with various other cardiometabolic risk factors (CMRFs). However, the direct causal relationship of IR with AN in obesity has been debated. There...

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Main Authors: Juan C Lopez-Alvarenga, Geetha Chittoor, Solomon F D Paul, Sobha Puppala, Vidya S Farook, Sharon P Fowler, Roy G Resendez, Joselin Hernandez-Ruiz, Alvaro Diaz-Badillo, David Salazar, Doreen D Garza, Donna M Lehman, Srinivas Mummidi, Rector Arya, Christopher P Jenkinson, Jane L Lynch, Ralph A DeFronzo, John Blangero, Daniel E Hale, Ravindranath Duggirala
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240467

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