The Plasticity of Th17 Cells in the Pathogenesis of Rheumatoid Arthritis

Helper T (Th) cells play an important role in the pathogenesis of autoimmune diseases, including rheumatoid arthritis (RA). It has been revealed that Th17 cells can shift to Th1 cells (i.e., “nonclassic Th1 cells”), which are reported to be more pathogenic than Th17 cells per se. Thus, the associati...

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Bibliographic Details
Main Authors: Shigeru Kotake, Toru Yago, Tsuyoshi Kobashigawa, Yuki Nanke
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/6/7/67