Pyrrole-protein adducts – A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity

Pyrrolizidine alkaloids (PAs) are phytotoxins identified in over 6000 plant species worldwide. Approximately 600 toxic PAs and PA N-oxides have been identified in about 3% flowering plants. PAs can cause toxicities in different organs particularly in the liver. The metabolic activation of PAs is cat...

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Bibliographic Details
Main Authors: Jiang Ma, Qingsu Xia, Peter P. Fu, Ge Lin
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Journal of Food and Drug Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1021949818300863