mTORC1 is essential for early steps during Schwann cell differentiation of amniotic fluid stem cells and regulates lipogenic gene expression.

mTORC1 is essential for early steps during Schwann cell differentiation of amniotic fluid stem cells and regulates lipogenic gene expression.

Schwann cell development is hallmarked by the induction of a lipogenic profile. Here we used amniotic fluid stem (AFS) cells and focused on the mechanisms occurring during early steps of differentiation along the Schwann cell lineage. Therefore, we initiated Schwann cell differentiation in AFS cells...

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Bibliographic Details
Main Authors: Andrea Preitschopf, Kongzhao Li, David Schörghofer, Katharina Kinslechner, Birgit Schütz, Ha Thi Thanh Pham, Margit Rosner, Gabor Jozsef Joo, Clemens Röhrl, Thomas Weichhart, Herbert Stangl, Gert Lubec, Markus Hengstschläger, Mario Mikula
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4164523?pdf=render

Internet

http://europepmc.org/articles/PMC4164523?pdf=render

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