Tissue specific induction of p62/Sqstm1 by farnesoid X receptor.

Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily and is a ligand-activated transcription factor essential for maintaining liver and intestinal homeostasis. FXR is protective against carcinogenesis and inflammation in liver and intestine as demonstrated by the development of...

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Bibliographic Details
Main Authors: Jessica A Williams, Ann M Thomas, Guodong Li, Bo Kong, Le Zhan, Yuka Inaba, Wen Xie, Wen-Xing Ding, Grace L Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3428273?pdf=render