Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice

Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice

Radix astragali, a medicinal material for tonifying Chinese Qi, has widely been used for the treatment of Kidney disease in China and East Asia, especially in reducing the apoptosis of glomerular podocytes. Paecilomyces Cicadidae is a medicinal and edible fungus. In recent years, the application of...

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Bibliographic Details
Main Authors: Fang Yang, Qingsong Qu, Chongyan Zhao, Xing Liu, Pengshuo Yang, Zhixun Li, Lu Han, Xinyuan Shi
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Radix astragali
Paecilomyces cicadae
Fermentation
Diabetic nephropathy
Podocytes
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220306727

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http://www.sciencedirect.com/science/article/pii/S0753332220306727

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