Expression in aneuploid Drosophila S2 cells.

Extensive departures from balanced gene dose in aneuploids are highly deleterious. However, we know very little about the relationship between gene copy number and expression in aneuploid cells. We determined copy number and transcript abundance (expression) genome-wide in Drosophila S2 cells by DNA...

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Bibliographic Details
Main Authors: Yu Zhang, John H Malone, Sara K Powell, Vipul Periwal, Eric Spana, David M Macalpine, Brian Oliver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2826376?pdf=render