Therapeutic effect of human iPS-cell-derived myeloid cells expressing IFN-β against peritoneally disseminated cancer in xenograft models.

Therapeutic effect of human iPS-cell-derived myeloid cells expressing IFN-β against peritoneally disseminated cancer in xenograft models.

We recently developed a method to generate myeloid cells with proliferation capacity from human iPS cells. iPS-ML (iPS-cell-derived myeloid/macrophage line), generated by introducing proliferation and anti-senescence factors into iPS-cell-derived myeloid cells, grew continuously in an M-CSF-dependen...

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Bibliographic Details
Main Authors: Chihiro Koba, Miwa Haruta, Yusuke Matsunaga, Keiko Matsumura, Eriko Haga, Yuko Sasaki, Tokunori Ikeda, Koutaro Takamatsu, Yasuharu Nishimura, Satoru Senju
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3691167?pdf=render

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http://europepmc.org/articles/PMC3691167?pdf=render

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