Role of tissue transglutaminase 2 in the acquisition of a mesenchymal-like phenotype in highly invasive A431 tumor cells

Role of tissue transglutaminase 2 in the acquisition of a mesenchymal-like phenotype in highly invasive A431 tumor cells

<p>Abstract</p> <p>Background</p> <p>Cancer progression is closely linked to the epithelial-mesenchymal transition (EMT) process. Studies have shown that there is increased expression of tissue tranglutaminase (TG2) in advanced invasive cancer cells. TG2 catalyzes the c...

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Bibliographic Details
Main Authors: Huang Chang-Jen, Cheng Chia-Hsiung, Chang Geen-Dong, Kandaswami Chithan C, Tsai Pei-Hsun, Lin Chun-Yu, Lee Ping-Ping, Hwang Jiuan-Jiuan, Lee Ming-Ting
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Molecular Cancer
Subjects:
epithelial-mesenchymal transition
tissue transglutaminase
matrix metalloproteinase
PI3K/Akt
NF-κB
Snail
migration
Online Access:http://www.molecular-cancer.com/content/10/1/87

Internet

http://www.molecular-cancer.com/content/10/1/87

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