Safety of Silk-elastin Sponges in Patients with Chronic Skin Ulcers: A Phase I/II, Single-center, Open-label, Single-arm Clinical Trial

Background:. Although traditional wound dressings such as collagen scaffolds promote granulation tissue formation, the efficacy of these dressings in chronic wounds is limited because of high susceptibility to bacterial growth. Biomaterials that can be applied to chronic wounds should have an anti-b...

Full description

Bibliographic Details
Main Authors: Kazuo Noda, MD, PhD, Katsuya Kawai, MD, PhD, Yoshitaka Matsuura, MD, Toshiko Ito-Ihara, MD, PhD, Yoko Amino, PharmD, Mika Ushimaru, PhD, Akemi Kinoshita, Harue Tada, PhD, Hiroyasu Abe, PhD, Satoshi Morita, PhD, Akira Shimizu, MD, PhD, Itaru Tsuge, MD, PhD, Michiharu Sakamoto, MD, PhD, Naoki Morimoto, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2021-04-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003556