Enhancing solubility of deoxyxylulose phosphate pathway enzymes for microbial isoprenoid production

<p>Abstract</p> <p>Background</p> <p>Recombinant proteins are routinely overexpressed in metabolic engineering. It is well known that some over-expressed heterologous recombinant enzymes are insoluble with little or no enzymatic activity. This study examined the solubil...

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Bibliographic Details
Main Authors: Zhou Kang, Zou Ruiyang, Stephanopoulos Gregory, Too Heng-Phon
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://www.microbialcellfactories.com/content/11/1/148