Amnion-Derived Teno-Inductive Secretomes: A Novel Approach to Foster Tendon Differentiation and Regeneration in an Ovine Model

Amnion-Derived Teno-Inductive Secretomes: A Novel Approach to Foster Tendon Differentiation and Regeneration in an Ovine Model

Regenerative medicine has greatly progressed, but tendon regeneration mechanisms and robust in vitro tendon differentiation protocols remain to be elucidated. Recently, tendon explant co-culture (CO) has been proposed as an in vitro model to recapitulate the microenvironment driving tendon developme...

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Bibliographic Details
Main Authors: Maria Rita Citeroni, Annunziata Mauro, Maria Camilla Ciardulli, Miriam Di Mattia, Mohammad El Khatib, Valentina Russo, Maura Turriani, Michael Santer, Giovanna Della Porta, Nicola Maffulli, Nicholas R. Forsyth, Barbara Barboni
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
amniotic stem cells
co-culture
conditioned media
tendon
tendon-differentiation
tissue engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.649288/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.649288/full

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