Overexpression of MAP3K3 promotes tumour growth through activation of the NF-κB signalling pathway in ovarian carcinoma

Abstract Mitogen-activated protein kinase kinase kinase 3 (MAP3K3), a member of the serine/threonine protein kinase family, is ubiquitously expressed and acts as an oncogene. However, the expression and exact molecular mechanism of MAP3K3 in ovarian carcinoma (OC) remain unclear. Here, we found that...

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Bibliographic Details
Main Authors: Ying Zhang, Sha-Sha Wang, Lin Tao, Li-Juan Pang, Hong Zou, Wei-Hua Liang, Zheng Liu, Su-Liang Guo, Jin-Fang Jiang, Wen-Jie Zhang, Wei Jia, Feng Li
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-44835-7