Alpha-1 Antitrypsin Z Variant (AAT PI*Z) as a Risk Factor for Intrahepatic Cholestasis of Pregnancy

Alpha-1 Antitrypsin Z Variant (AAT PI*Z) as a Risk Factor for Intrahepatic Cholestasis of Pregnancy

Background: Intrahepatic cholestasis of pregnancy (ICP; prevalence 0.2–15.6%) is the most common pregnancy-related liver disorder. It may have serious consequences for a pregnancy, including increased risk of preterm delivery, meconium staining of amniotic fluid, fetal bradycardia, distress, and fet...

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Main Authors: Przemyslaw Kosinski, Malgorzata Kedzia, Adrianna Mostowska, Pawel Gutaj, Michal Lipa, Ewa Wender-Ozegowska, Adriana Rozy, Joanna Chorostowska-Wynimko, Miroslaw Wielgos, Aleksandra Jezela-Stanek
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
ursodeoxycholic acid
alpha-1 antitrypsin deficiency
intrahepatic cholestasis of pregnancy
cholestasis
pregnancy
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.720465/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.720465/full

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