Synchrotron X-Ray Radiation-Induced Bystander Effect: An Impact of the Scattered Radiation, Distance From the Irradiated Site and p53 Cell Status

Synchrotron X-Ray Radiation-Induced Bystander Effect: An Impact of the Scattered Radiation, Distance From the Irradiated Site and p53 Cell Status

Synchrotron radiation, especially microbeam radiotherapy (MRT), has a great potential to improve cancer radiotherapy, but non-targeted effects of synchrotron radiation have not yet been sufficiently explored. We have previously demonstrated that scattered synchrotron radiation induces measurable γ-H...

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Bibliographic Details
Main Authors: Pavel Lobachevsky, Helen B. Forrester, Alesia Ivashkevich, Joel Mason, Andrew W. Stevenson, Chris J. Hall, Carl N. Sprung, Valentin G. Djonov, Olga A. Martin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
synchrotron radiation
microbeam radiation therapy (MRT)
scattered radiation
radiation induced bystander effect (RIBE)
DNA damage
gamma-H2AX (γH2AX)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.685598/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.685598/full

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