Single dose rVSVΔG-JUNVGP vaccine protects guinea pigs against lethal Junin virus challenge

Abstract Junin virus (JUNV) is a pathogen of biodefense importance due to its potential for aerosol transmission and mortality rates reaching 30%. Currently, there are no JUNV vaccines licensed by the United States Food and Drug Administration (FDA) for at-risk individuals. A vaccine based on recomb...

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Bibliographic Details
Main Authors: Teresa E. Sorvillo, Robert W. Cross, Dylan M. Johnson, Natalie S. Dobias, Karla A. Fenton, Chad E. Mire, Thomas W. Geisbert
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00361-0