Campylobacter jejuni pdxA affects flagellum-mediated motility to alter host colonization.

Vitamin B6 (pyridoxal-5'-phosphate, PLP) is linked to a variety of biological functions in prokaryotes. Here, we report that the pdxA (putative 4-hydroxy-L-threonine phosphate dehydrogenase) gene plays a pivotal role in the PLP-dependent regulation of flagellar motility, thereby altering host c...

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Bibliographic Details
Main Authors: Hiroshi Asakura, Noritaka Hashii, Masashi Uema, Nana Kawasaki, Yoshiko Sugita-Konishi, Shizunobu Igimi, Shigeki Yamamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3735588?pdf=render