Langerhans cells in hypospadias: an analysis of Langerin (CD207) and HLA-DR on epidermal sheets and full thickness skin sections

Abstract Background Hypospadias are among the most common genital malformations. Langerhans Cells (LCs) play a pivotal role in HIV and HPV infection. The migration of LC precursors to skin coincides with the embryonic period of hypospadias development and genetic alterations leading to the formation...

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Bibliographic Details
Main Authors: Bernhard Haid, Daniela Reider, Felix Nägele, Anne-Françoise Spinoit, Elisabeth Pechriggl, Nikolaus Romani, Helga Fritsch, Josef Oswald
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Urology
Subjects:
HPV
HIV
Online Access:http://link.springer.com/article/10.1186/s12894-019-0551-8