Methylprednisolone stiffens aortas in lipopolysaccharide-induced chronic inflammation in rats.

INTRODUCTION: Glucocorticoids are commonly used as therapeutic agents in many acute and chronic inflammatory and auto-immune diseases. The current study investigated the effects of methylprednisolone (a synthetic glucocorticoid) on aortic distensibility and vascular resistance in lipopolysaccharide-...

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Bibliographic Details
Main Authors: Ya-Hui Ko, Ming-Shian Tsai, Po-Huang Lee, Jin-Tung Liang, Kuo-Chu Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3714265?pdf=render