Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration

There are a vast number of neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD), associated with the rearrangement of specific proteins to non-native conformations that promotes aggregation and deposition within tissues and/or cellul...

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Bibliographic Details
Main Authors: Kathleen A Burke, Elizabeth A Yates, Justin eLegleiter
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00017/full