Approaching the functional annotation of fungal virulence factors using cross-species genetic interaction profiling.

In many human fungal pathogens, genes required for disease remain largely unannotated, limiting the impact of virulence gene discovery efforts. We tested the utility of a cross-species genetic interaction profiling approach to obtain clues to the molecular function of unannotated pathogenicity facto...

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Bibliographic Details
Main Authors: Jessica C S Brown, Hiten D Madhani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3531484?pdf=render