Exome sequencing and linkage analysis identified tenascin-C (TNC) as a novel causative gene in nonsyndromic hearing loss.

Exome sequencing and linkage analysis identified tenascin-C (TNC) as a novel causative gene in nonsyndromic hearing loss.

In this study, a five-generation Chinese family (family F013) with progressive autosomal dominant hearing loss was mapped to a critical region spanning 28.54 Mb on chromosome 9q31.3-q34.3 by linkage analysis, which was a novel DFNA locus, assigned as DFNA56. In this interval, there were 398 annotate...

Full description

Bibliographic Details
Main Authors: Yali Zhao, Feifan Zhao, Liang Zong, Peng Zhang, Liping Guan, Jianguo Zhang, Dayong Wang, Jing Wang, Wei Chai, Lan Lan, Qian Li, Bing Han, Ling Yang, Xin Jin, Weiyan Yang, Xiaoxiang Hu, Xiaoning Wang, Ning Li, Yingrui Li, Christine Petit, Jun Wang, Huanming Yang Jian Wang, Qiuju Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3728356?pdf=render

Internet

http://europepmc.org/articles/PMC3728356?pdf=render

Similar Items