Ancient human miRNAs are more likely to have broad functions and disease associations than young miRNAs

Ancient human miRNAs are more likely to have broad functions and disease associations than young miRNAs

Abstract Background microRNAs (miRNAs) are essential to the regulation of gene expression in eukaryotes, and improper expression of miRNAs contributes to hundreds of diseases. Despite the essential functions of miRNAs, the evolutionary dynamics of how they are integrated into existing gene regulator...

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Bibliographic Details
Main Authors: Vir D. Patel, John A. Capra
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Genomics
Subjects:
miRNA evolution
Human disease
Phylogenetics
Gene regulation
Online Access:http://link.springer.com/article/10.1186/s12864-017-4073-z

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http://link.springer.com/article/10.1186/s12864-017-4073-z

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