Ancient human miRNAs are more likely to have broad functions and disease associations than young miRNAs
Abstract Background microRNAs (miRNAs) are essential to the regulation of gene expression in eukaryotes, and improper expression of miRNAs contributes to hundreds of diseases. Despite the essential functions of miRNAs, the evolutionary dynamics of how they are integrated into existing gene regulator...
Main Authors: | Vir D. Patel, John A. Capra |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-08-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-017-4073-z |
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